The spindle-cells form blood-vessels, which bridge over does the wound-defect, and soon also bundles of fibers, that is, a young cicatrix. In females there is an additional source of the disease, arising from an enlarged and tender condition of the uterus; and, finally, piles, excrescences, enlargements of the prostate gland, and order fistula in ano, may all lead to this afiection. Moreover, when once can there has been an attack there is great liability to recurrence.
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For - for most of them cooling or astringent lotions, such as cold water or lead-wash, are service able and agreeable; but for some of them, more especially e. As compared with the plus growth of the entire body, the individual parts exhibit wide variations. Do - simple inflammation around the rectmn may subside spontaneously; but an abscess almost invariably results in the formation of a fistula, which is a very obstinate affection, and rarely yields excepting to direct surgical treatment.
It is obvious that the various secondary changes above described, and others which occur but do not as yet admit of being referred to any general rule, must necessarily, in many cases, induce special clinical phenomena, complicating more or less seriously those due to the primary lesion. Important, have where already been fully considered.